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Case Reports
. 2017 Apr-Jun;48(2):208-210.
doi: 10.1016/j.bjm.2016.02.001. Epub 2016 Dec 22.

Oral phaeohyphomycosis in a patient with squamocellular carcinoma of the lip: second case report

Suanni Lemos de Andrade  1 , André Ferraz Goiana Leal  2 , Armando Marsden Lacerda Filho  3 , Danielle Patrícia Cerqueira Macêdo  3 , Maria do Carmo Carvalho de Abreu E Lima  4 , Rejane Pereira Neves  3
Affiliations
Case Reports

Oral phaeohyphomycosis in a patient with squamocellular carcinoma of the lip: second case report

Suanni Lemos de Andrade et al. Braz J Microbiol. 2017 Apr-Jun.

Abstract

This communication reports the second known case of oral phaeohyphomycosis in a patient with squamocellular carcinoma of the lip. The patient, an 82-year-old black woman, a former smoker (for more than 30 years), suffering from an ulcerous vegetative lesion in the middle third of the lower lip for approximately 12 months. The result of the histopathological analysis indicated carcinoma, with well-differentiated keratinized squamous cells and the presence of septate mycelial filaments. In the direct mycological examination, thick and dematiaceous septate mycelial filaments were observed. After the resection surgery, the patient did not need to use an antifungal drug to treat the phaeohyphomycosis, and no follow-up radiotherapy was needed to treat the squamocellular carcinoma. We stress that the presence of the squamocellular lesion of the lip was a possible contributing factor to the infection.

Keywords: Lip; Oral phaeohyphomycosis; Squamocellular carcinoma.

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Figures

Fig. 1
Fig. 1
(A) Ulcerative lesion of the lower lip. (B) View of the lower lip after surgical resection of the lesion.
Fig. 2
Fig. 2
Direct mycological examination: clinical sample clarified with 20% KOH, exhibiting thick and dematiaceous septate mycelial filaments.
See this image and copyright information in PMC

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