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. 2016 Nov-Dec;49(6):382-388.
doi: 10.1590/0100-3984.2015.0033.

T1-weighted gradient-echo imaging, with and without inversion recovery, in the identification of anatomical structures on the lateral surface of the brain

Sergio Murilo Georgeto  1 , Carlos Alexandre Martins Zicarelli  1 , Munir Antônio Gariba  2 , Luiz Roberto Aguiar  2
Affiliations

T1-weighted gradient-echo imaging, with and without inversion recovery, in the identification of anatomical structures on the lateral surface of the brain

Sergio Murilo Georgeto et al. Radiol Bras. 2016 Nov-Dec.

Abstract
in English, Portuguese

Objective: To compare brain structures using volumetric magnetic resonance imaging with isotropic resolution, in T1-weighted gradient-echo (GRE) acquisition, with and without inversion recovery (IR).

Materials and methods: From 30 individuals, we evaluated 120 blocks of images of the left and right cerebral hemispheres being acquired by T1 GRE and by T1 IR GRE. On the basis of the Naidich et al. method for localization of anatomical landmarks, 27 anatomical structures were divided into two categories: identifiable and inconclusive. Those two categories were used in the analyses of repeatability (intraobserver agreement) and reproducibility (interobserver agreement). McNemar's test was used in order to compare the T1 GRE and T1 IR GRE techniques.

Results: There was good agreement in the intraobserver and interobserver analyses (mean kappa > 0.60). McNemar's test showed that the frequency of identifiable anatomical landmarks was slightly higher when the T1 IR GRE technique was employed than when the T1 GRE technique was employed. The difference between the two techniques was statistically significant.

Conclusion: In the identification of anatomical landmarks, the T1 IR GRE technique appears to perform slightly better than does the T1 GRE technique.

Objetivo: Comparar os resultados de identificação de estruturas cerebrais utilizando imagens volumétricas isotrópicas por ressonância magnética, nas aquisições T1 GRE e T1 IR GRE.

Materiais e métodos: Foram avaliados 120 blocos de imagens, de 30 indivíduos, com imagens extraídas dos hemisférios cerebrais esquerdo e direito, pelos dois métodos de aquisição: T1 GRE e T1 IR GRE. Com base no método de Naidich et al. para localização dos referenciais anatômicos, 27 estruturas anatômicas foram classificadas em duas categorias - identificável versus deixam dúvidas quanto à identificação somadas às não identificáveis - para análises de repetitividade (intraobservador) e reprodutibilidade (interobservadores). Foi utilizado o teste de McNemar para a avaliação do desempenho entre os dois métodos.

Resultados: Após confirmação de ter havido boa concordância na análise intraobservador e interobservadores (kappa médio > 0,60), a avaliação das imagens de cada referencial anatômico, testada entre T1 GRE e T1 IR GRE pelo teste de McNemar, indicou maior frequência de referenciais identificáveis pelo método T1 IR GRE do que pelo método T1 GRE.

Conclusão: O método de imagem T1 IR GRE apresentou desempenho levemente superior, porém estatisticamente significante, em relação ao método T1 GRE, na identificação dos referenciais anatômicos cerebrais.

Keywords: Brain/anatomy & histology; Magnetic resonance imaging; Reproducibility of results.

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Figures

Figure 1
Figure 1
Sagittal images of the lateral fissure at its deepest extent, obtained with the T1 GRE (A) and T1 IR GRE (B) techniques.
See this image and copyright information in PMC

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