Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Dec 24;6(4):767-773.
doi: 10.5500/wjt.v6.i4.767.

Systematic review of the negative pressure wound therapy in kidney transplant recipients

Badri Man Shrestha  1
Affiliations

Systematic review of the negative pressure wound therapy in kidney transplant recipients

Badri Man Shrestha. World J Transplant. .

Abstract

Aim: To review negative pressure wound therapy (NPWT) as an important addition to the conventional methods of wound management.

Methods: A systematic review, performed by searching the PubMed, EMBASE and Cochrane Library databases, showed 11 case reports comprising a total of 22 kidney transplantation (KT) patients (range, 1 to 9), who were treated with NPWT. Application of NPWT was associated with successful healing of wounds, leg ulcer, lymphocele and urine leak from ileal conduit.

Results: No complications related to NPWT were reported. However, there was paucity of robust data on the effectiveness of NPWT in KT recipients; therefore, prospective studies assessing its safety and efficacy of NPWT and randomised trials comparing the effectiveness of NPWT with alternative modalities of wound management in KT recipients is recommended.

Conclusion: Negative pressure incision management system, NPWT with instillation and endoscopic vacuum-assisted closure system are in investigational stage.

Keywords: Kidney transplantation; Negative pressure; Wound dehiscence; Wound infection; Wound therapy.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: Part of the manuscript was published elsewhere (http://researchpub.org/journal/npwt/archives-vol1-no2.html) in 2014, but was retracted by the author. There is no conflict of interest involved.

Figures

Figure 1
Figure 1
Negative pressure wound therapy device and its components. A: Black polyurethane foam dressing and tubing in the wound; B: Canister containing exudates; C: Standard suction device; D: Portable suction device.
See this image and copyright information in PMC

References

    1. Shrestha A, Shrestha A, Basarab-Horwath C, McKane W, Shrestha B, Raftery A. Quality of life following live donor renal transplantation: a single centre experience. Ann Transplant. 2010;15:5–10. - PubMed
    1. Harris AD, Fleming B, Bromberg JS, Rock P, Nkonge G, Emerick M, Harris-Williams M, Thom KA. Surgical site infection after renal transplantation. Infect Control Hosp Epidemiol. 2015;36:417–423. - PMC - PubMed
    1. Nashan B, Citterio F. Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature. Transplantation. 2012;94:547–561. - PubMed
    1. Judson RT. Wound infection following renal transplantation. Aust N Z J Surg. 1984;54:223–224. - PubMed
    1. Dean PG, Lund WJ, Larson TS, Prieto M, Nyberg SL, Ishitani MB, Kremers WK, Stegall MD. Wound-healing complications after kidney transplantation: a prospective, randomized comparison of sirolimus and tacrolimus. Transplantation. 2004;77:1555–1561. - PubMed

LinkOut - more resources