Exosomal Small Talk Carries Strong Messages from Muscle Stem Cells
- PMID: 28061348
- DOI: 10.1016/j.stem.2016.12.009
Exosomal Small Talk Carries Strong Messages from Muscle Stem Cells
Abstract
Exosome-dependent intercellular communication is an emerging signaling mechanism involved in tissue repair and regeneration. Now in this issue of Cell Stem Cell, Fry et al. (2016) show that muscle stem cells communicate with fibrogenic cells by exosomal trafficking of microRNA-206 to regulate extracellular matrix deposition and muscle tissue remodeling.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy.Cell Stem Cell. 2017 Jan 5;20(1):56-69. doi: 10.1016/j.stem.2016.09.010. Epub 2016 Nov 10. Cell Stem Cell. 2017. PMID: 27840022 Free PMC article.
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