New Treatments for Hair Loss

Abstract

The treatment of hair loss is an important part of clinical dermatology given the prevalence of the problem and great impact on patients' quality of life. Many new treatments have been introduced in recent years. This review summarizes the main ones in 4 groups: a) For androgenetic alopecia, we discuss new excipients for oral minoxidil, dutasteride, and finasteride as well as new forms of topical application; prostaglandin agonists and antagonists; low-level laser therapy; and regenerative medicine with Wnt signaling activators and stem cell therapy. b) For alopecia areata, Janus kinase inhibitors are reviewed. c) For frontal fibrosing alopecia, we discuss the use of antiandrogens and, for some patients, pioglitazone. d) Finally, we mention new robotic devices for hair transplant procedures and techniques for optimal follicular unit extraction.

Keywords: Alopecia androgénica; Alopecia areata; Alopecia frontal fibrosante; Androgenetic alopecia; Dutasterida; Dutasteride; Frontal fibrosing alopecia; Hair loss treatments; Low-level laser therapy; Láser de baja potencia; Ruxolitinib; Tricología; Vía Wnt; Wnt pathway.