Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989;15(10):665-9.
doi: 10.1007/BF00251681.

Metabolic fate of L-[methyl-11C]methionine in human plasma

K Ishiwata  1 , J Hatazawa, K Kubota, M Kameyama, M Itoh, T Matsuzawa, T Takahashi, R Iwata, T Ido
Affiliations

Metabolic fate of L-[methyl-11C]methionine in human plasma

K Ishiwata et al. Eur J Nucl Med. 1989.

Abstract

The metabolites of L-[methyl-11C]methionine in the plasma of 8 patients with tumors were measured for 60 min after injection. In the plasma, after a rapid clearance, the total radioactivity remained constant, and protein-bound radioactivity increased rapidly. Non protein metabolites detected by HPLC as at least two components besides methionine, increased with time. Significant individual variations for the metabolism were observed. At 60 min after injection, 36.5% (range: 16%-72%) and 45.3% (range: 13%-74%) of the 11C was measured as methionine and labeled proteins, respectively.

PubMed Disclaimer

References

    1. J Neurooncol. 1986;3(4):397-404 - PubMed
    1. AJNR Am J Neuroradiol. 1985 Jul-Aug;6(4):505-14 - PubMed
    1. J Nutr. 1974 Jun;104(6):761-71 - PubMed
    1. Proc Natl Acad Sci U S A. 1976 May;73(5):1523-7 - PubMed
    1. Int J Rad Appl Instrum A. 1988;39(4):311-4 - PubMed