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Comment
. 2017 Mar;33(3):156-158.
doi: 10.1016/j.pt.2016.12.008. Epub 2017 Jan 6.

Oral, Slow-Release Ivermectin: Biting Back at Malaria Vectors

Carlos J Chaccour  1 , N Regina Rabinovich  2
Affiliations
Comment

Oral, Slow-Release Ivermectin: Biting Back at Malaria Vectors

Carlos J Chaccour et al. Trends Parasitol. 2017 Mar.

Abstract

Bellinger and colleagues offer an elegant twist for a promising new tool against malaria. This formulation is designed to release ivermectin, a mosquito-killing drug for 10 days after a single oral dose. This could reduce the vector population and serve as a complementary tool for malaria elimination.

Keywords: endectocide; ivermectin; malaria elimination; mass drug administration; slow-release; vector control.

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  • Oral, ultra-long-lasting drug delivery: Application toward malaria elimination goals.
    Bellinger AM, Jafari M, Grant TM, Zhang S, Slater HC, Wenger EA, Mo S, Lee YL, Mazdiyasni H, Kogan L, Barman R, Cleveland C, Booth L, Bensel T, Minahan D, Hurowitz HM, Tai T, Daily J, Nikolic B, Wood L, Eckhoff PA, Langer R, Traverso G. Bellinger AM, et al. Sci Transl Med. 2016 Nov 16;8(365):365ra157. doi: 10.1126/scitranslmed.aag2374. Sci Transl Med. 2016. PMID: 27856796 Free PMC article.

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