Urinary bladder cancer in adults: a histopathological experience from Madinah, Saudi Arabia

Abstract

Objective: To delineate the frequency and clinicopathological features of urinary bladder cancer.

Methods: This retrospective study was conducted at the King Fahd Hospital, Madinah, Saudi Arabia, and comprised medical records related to bladder tumours, from January 2006 to October 2015. Data was obtained from histopathologic reports and evaluated for age, gender, cystoscopic findings and histopathological characteristics at the time of presentation.

Results: Of the 116 cases, 96(82.7%) were of men while 20(17.3%) were of women. The mean age was 62.4±15.62 years (range: 20-115 years). Transitional cell carcinoma was the most common histological type, seen in 111(95.7%) cases, followed by adenocarcinoma 3(2.6%) and squamous cell carcinoma 2(1.7%). Of the transitional cell carcinoma cases, 78(70.5%) were superficial, while 33(29.5%) were muscle invasive. Most of the transitional cell carcinoma cases 72(65%) were of lower grade (grade I and II), while 39(35%) were of grade III.

Conclusions: Our hospital-based pathology experience of urinary bladder cancer was comparable with earlier studies.

Keywords: Urinary bladder cancer, Transitional cell carcinoma, Histopathology, Madinah, Saudi Arabia..