Authors' response to commentaries on rosuvastatin for delirium and cognitive impairment in sepsis-associated acute respiratory distress syndrome

Victor D Dinglas¹, Elizabeth Colantuoni², E Wesley Ely³, Catherine L Hough⁴, Peter E Morris⁵, Pedro A Mendez-Tellez⁶, Amy W Wozniak², Ramona O Hopkins⁷, Dale M Needham⁸

Affiliations

¹ Outcomes after Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, Maryland, USA;; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
² Outcomes after Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, Maryland, USA;; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
³ Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA;; Geriatric Research, Education and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA.
⁴ Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA.
⁵ Division of Pulmonary, Critical Care & Sleep Medicine, University of Kentucky, Lexington, KY, USA.
⁶ Outcomes after Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, Maryland, USA;; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
⁷ Division of Pulmonary and Critical Care, Department of Medicine, Intermountain Medical Center, Murray, Utah, USA;; Psychology Department and Neuroscience Center, Brigham Young University, Provo, Utah.
⁸ Outcomes after Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, Maryland, USA;; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;; Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

PMID: 28066653
PMCID: PMC5179448
DOI: 10.21037/jtd.2016.11.53

Comment

Authors' response to commentaries on rosuvastatin for delirium and cognitive impairment in sepsis-associated acute respiratory distress syndrome

Victor D Dinglas et al. J Thorac Dis. 2016 Nov.

. 2016 Nov;8(11):E1534-E1536.

doi: 10.21037/jtd.2016.11.53.

Authors

Victor D Dinglas¹, Elizabeth Colantuoni², E Wesley Ely³, Catherine L Hough⁴, Peter E Morris⁵, Pedro A Mendez-Tellez⁶, Amy W Wozniak², Ramona O Hopkins⁷, Dale M Needham⁸

Affiliations

¹ Outcomes after Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, Maryland, USA;; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
² Outcomes after Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, Maryland, USA;; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
³ Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA;; Geriatric Research, Education and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA.
⁴ Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle, WA, USA.
⁵ Division of Pulmonary, Critical Care & Sleep Medicine, University of Kentucky, Lexington, KY, USA.
⁶ Outcomes after Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, Maryland, USA;; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
⁷ Division of Pulmonary and Critical Care, Department of Medicine, Intermountain Medical Center, Murray, Utah, USA;; Psychology Department and Neuroscience Center, Brigham Young University, Provo, Utah.
⁸ Outcomes after Critical Illness and Surgery (OACIS) Group, Johns Hopkins University, Baltimore, Maryland, USA;; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;; Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

PMID: 28066653
PMCID: PMC5179448
DOI: 10.21037/jtd.2016.11.53

No abstract available

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Comment on

Association of rosuvastatin and delirium in severe sepsis with acute respiratory distress syndrome.
Pourafkari L, Nader ND, Porhomayon J. Pourafkari L, et al. J Thorac Dis. 2016 Aug;8(8):E775-7. doi: 10.21037/jtd.2016.05.82. J Thorac Dis. 2016. PMID: 27618838 Free PMC article. No abstract available.
Statins for delirium in ICU patients: a negative trial but a positive step.
Lange PW, Maier AB. Lange PW, et al. J Thorac Dis. 2016 Sep;8(9):E1063-E1066. doi: 10.21037/jtd.2016.08.33. J Thorac Dis. 2016. PMID: 27747064 Free PMC article. No abstract available.

References

1. Lange PW, Maier AB. Statins for delirium in ICU patients: a negative trial but a positive step. J Thorac Dis 2016;8:E1063-E1066. 10.21037/jtd.2016.08.33 - DOI - PMC - PubMed
1. Pourafkari L, Nader ND, Porhomayon J. Association of rosuvastatin and delirium in severe sepsis with acute respiratory distress syndrome. J Thorac Dis 2016;8:E775-7. 10.21037/jtd.2016.05.82 - DOI - PMC - PubMed
1. Needham DM, Colantuoni E, Dinglas VD, et al. Rosuvastatin versus placebo for delirium in intensive care and subsequent cognitive impairment in patients with sepsis-associated acute respiratory distress syndrome: an ancillary study to a randomised controlled trial. Lancet Respir Med 2016;4:203-12. 10.1016/S2213-2600(16)00005-9 - DOI - PMC - PubMed
1. Wassenaar A, van den Boogaard M, van Achterberg T, et al. Multinational development and validation of an early prediction model for delirium in ICU patients. Intensive Care Med 2015;41:1048-56. 10.1007/s00134-015-3777-2 - DOI - PMC - PubMed
1. Colantuoni E, Dinglas VD, Ely EW, et al. Statistical methods for evaluating delirium in the ICU. Lancet Respir Med 2016;4:534-6. 10.1016/S2213-2600(16)30138-2 - DOI - PubMed

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Authors' response to commentaries on rosuvastatin for delirium and cognitive impairment in sepsis-associated acute respiratory distress syndrome

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Authors' response to commentaries on rosuvastatin for delirium and cognitive impairment in sepsis-associated acute respiratory distress syndrome

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