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Review
. 2016 Oct;8(Suppl 9):S738-S743.
doi: 10.21037/jtd.2016.09.49.

Applications of indocyanine green based near-infrared fluorescence imaging in thoracic surgery

Jian Zhou  1 , Fan Yang  1 , Guanchao Jiang  1 , Jun Wang  1
Affiliations
Review

Applications of indocyanine green based near-infrared fluorescence imaging in thoracic surgery

Jian Zhou et al. J Thorac Dis. 2016 Oct.

Abstract

Near-infrared (NIR) fluorescence guided surgery is an emerging technique. This technique uses the combination of dyes and NIR imaging devices to expand the visible spectrum. Thus it can provide more anatomic and functional information, and may facilitate a more complete resection of cancer, or better protection of important normal structures. Recently, significant progress has been made in the field of NIR fluorescence guided thoracic surgery. This may lead to better prognosis and health-economic outcomes. In this article, the current studies of indocyanine green (ICG) based NIR fluorescence guided thoracic surgeries are reviewed. The applications are classified into four categories, which are applications based on blood supply, lymphatic drainage, the enhanced permeability and retention (EPR) effect, and the other mechanisms.

Keywords: Near-infrared fluorescence; blood supply; enhanced permeability and retention effect (EPR effect); indocyanine green (ICG); lymphatic drainage.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

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