E-cadherin adhesion-mediated Wnt activation for mesoderm specification in human embryonic stem cells needs a soft mattress

Affiliations

¹ Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
² Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada;; Ottawa Institute of Systems Biology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada;; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada.

Comment

Andrew Sulaiman et al. Stem Cell Investig. 2016.

. 2016 Nov 14:3:77.

doi: 10.21037/sci.2016.10.12. eCollection 2016.

¹ Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
² Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada;; Ottawa Institute of Systems Biology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada;; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada.

No abstract available

Conflict of interest statement

The authors have no conflicts of interest to declare.

Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation.
Przybyla L, Lakins JN, Weaver VM. Przybyla L, et al. Cell Stem Cell. 2016 Oct 6;19(4):462-475. doi: 10.1016/j.stem.2016.06.018. Epub 2016 Jul 21. Cell Stem Cell. 2016. PMID: 27452175 Free PMC article.

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