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Review
. 2017 Jan 5;9(1):38.
doi: 10.3390/nu9010038.

Dietary Patterns and Pancreatic Cancer Risk: A Meta-Analysis

Pei-Ying Lu  1 , Long Shu  2 , Shan-Shan Shen  3 , Xu-Jiao Chen  4 , Xiao-Yan Zhang  5
Affiliations
Review

Dietary Patterns and Pancreatic Cancer Risk: A Meta-Analysis

Pei-Ying Lu et al. Nutrients. .

Abstract

A number of studies have examined the associations between dietary patterns and pancreatic cancer risk, but the findings have been inconclusive. Herein, we conducted this meta-analysis to assess the associations between dietary patterns and the risk of pancreatic cancer. MEDLINE (provided by the National Library of Medicine) and EBSCO (Elton B. Stephens Company) databases were searched for relevant articles published up to May 2016 that identified common dietary patterns. Thirty-two studies met the inclusion criteria and were finally included in this meta-analysis. A reduced risk of pancreatic cancer was shown for the highest compared with the lowest categories of healthy patterns (odds ratio, OR = 0.86; 95% confidence interval, CI: 0.77-0.95; p = 0.004) and light-moderate drinking patterns (OR = 0.90; 95% CI: 0.83-0.98; p = 0.02). There was evidence of an increased risk for pancreatic cancer in the highest compared with the lowest categories of western-type pattern (OR = 1.24; 95% CI: 1.06-1.45; p = 0.008) and heavy drinking pattern (OR = 1.29; 95% CI: 1.10-1.48; p = 0.002). The results of this meta-analysis demonstrate that healthy and light-moderate drinking patterns may decrease the risk of pancreatic cancer, whereas western-type and heavy drinking patterns may increase the risk of pancreatic cancer. Additional prospective studies are needed to confirm these findings.

Keywords: alcohol consumption; dietary patterns; meta-analysis; pancreatic cancer.

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Conflict of interest statement

The authors declared no conflict of interest.

Figures

Figure 1
Figure 1
Flow chart of article screening and selection process.
Figure 2
Figure 2
Forest plot for odds ratios (ORs) of the highest compared with the lowest category of intake of the healthy pattern and pancreatic cancer. CI: confidence interval.
Figure 3
Figure 3
Forest plot for ORs of the highest compared with the lowest category of intake of the western-type pattern and pancreatic cancer.
Figure 4
Figure 4
Forest plot for ORs of the highest compared with the lowest category of intake of the heavy drinking pattern and pancreatic cancer.
Figure 5
Figure 5
Forest plot for ORs of light–moderate drinking compared with non-drinking intake of the light–moderate drinking pattern and pancreatic cancer.
See this image and copyright information in PMC

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