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. 2016:2016:6583216.
doi: 10.1155/2016/6583216. Epub 2016 Dec 14.

Drug-Induced Sleep Endoscopy Changes the Treatment Concept in Patients with Obstructive Sleep Apnoea

Jaroslava Hybášková  1 , Ondřej Jor  2 , Vilém Novák  3 , Karol Zeleník  4 , Petr Matoušek  4 , Pavel Komínek  4
Affiliations

Drug-Induced Sleep Endoscopy Changes the Treatment Concept in Patients with Obstructive Sleep Apnoea

Jaroslava Hybášková et al. Biomed Res Int. 2016.

Abstract

The present study evaluated whether drug-induced sleep endoscopy (DISE) helps identify the site of obstruction in patients with obstructive sleep apnoea (OSA). A total of 51 consecutive patients with polysomnography-confirmed OSA were enrolled in this prospective study. The presumed site of obstruction was determined according to history, otorhinolaryngologic examination, and polysomnography and a therapeutic plan designed before DISE. In 11 patients with severe OSA and/or previously failed continuous positive airway pressure (CPAP) treatment, DISE with simultaneous CPAP was performed. Multilevel collapse was noted in 49 patients (96.1%). The most frequent multilevel collapse was palatal, oropharyngeal, and tongue base collapse (n = 17, 33.3%), followed by palatal and oropharyngeal collapse (n = 12, 23.5%). Pathology of the larynx (epiglottis) was observed in 16 patients (31.4%). The laryngeal obstruction as a reason for intolerance of CPAP was observed in 3/11 (27.3%) patients. After DISE, the surgical plan was changed in 31 patients (60.8%). The results indicate that DISE helps identify the site of obstruction in the upper airways in patients with OSA more accurately and that the larynx plays an important role in OSA.

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Conflict of interest statement

The authors declare that there is no actual or potential conflict of interests in relation to this article. No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.

Figures

Figure 1
Figure 1
Drug-induced sleep endoscopy with CPAP.
Figure 2
Figure 2
Collapsed epiglottis on the posterior wall of the hypopharynx during drug-induced sleep endoscopy. The condition caused apnoea.
See this image and copyright information in PMC

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