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. 2016 Oct;5(1):20-25.

Trace Elements Status in Sera of Patients with Allergic Asthma

Nazila Ariaee  1 , Reza Farid  1 , Fahimeh Shabestari  1 , Mohamad Shabestari  1 , Farahzad Jabbari Azad  1
Affiliations

Trace Elements Status in Sera of Patients with Allergic Asthma

Nazila Ariaee et al. Rep Biochem Mol Biol. 2016 Oct.

Abstract

Background: Asthma is a multifactorial disease and its severity varies with the inflammatory grade. There are conflicting reports about the roles of trace elements in asthma. This study examined the effects of zinc (Zn), copper (Cu), and selenium (Se) concentrations in sera of patients with allergic asthma attending Ghaem Hospital, Mashhad, Iran.

Methods: Forty-nine patients, aged 10 to 50 years, with asthma in moderate or severe stages, and 24 healthy controls, were enrolled in this study. After demographic data collection and clinical evaluations, the subjects' serum concentrations of Zn, Cu, and Se were measured via atomic absorbency.

Results: Mean serum levels of Zn and Se in patients with allergic asthma were lower than in the healthy control group, but the Cu concentration in sera of patients with allergic asthma was slightly higher than healthy controls.

Conclusion: Low levels of trace elements, specifically Zn, may have a role in the pathogenesis of allergic asthma; replacement of these elements may be an effective treatment.

Keywords: Asthma; Hyper sensitivity; Trace elements.

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Figures

Fig. 1
Fig. 1
Se concentrations in sera of patients with allergic asthma and healthy control groups, genders were considered distinctly. The Se concentration in male and females of healthy group was higher than patients both gender but not statistically was not significant. P value>.01
Fig. 2
Fig. 2
Zn concentrations in sera of patients with allergic asthma and healthy control groups, both genders in two groups were distinctly calculated. The Zn concentration in male and females of healthy group was higher than patients in both gender and it was statistically significant. P value>.01
Fig. 3
Fig. 3
Cu concentrations in sera with patients with allergic asthma and healthy control groups both genders in two group were distinctly calculated. The Cu concentration in females of patients group was higher than healthy group and it was statistically significant. P value>.01
See this image and copyright information in PMC

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