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. 2017 Jan 9;27(1):R24-R25.
doi: 10.1016/j.cub.2016.11.035.

Cell Migration: Making the Waves

Jan Müller  1 , Michael Sixt  2
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Free article
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Cell Migration: Making the Waves

Jan Müller et al. Curr Biol. .
Free article

Abstract

Coordinated changes of cell shape are often the result of the excitable, wave-like dynamics of the actin cytoskeleton. New work shows that, in migrating cells, protrusion waves arise from mechanochemical crosstalk between adhesion sites, membrane tension and the actin protrusive machinery.

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