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Review
. 2016 Apr:54:98-111.
doi: 10.1016/j.hal.2015.11.002.

The genetics, biosynthesis and regulation of toxic specialized metabolites of cyanobacteria

Leanne A Pearson  1 , Elke Dittmann  2 , Rabia Mazmouz  1 , Sarah E Ongley  1 , Paul M D'Agostino  1 , Brett A Neilan  3
Affiliations
Review

The genetics, biosynthesis and regulation of toxic specialized metabolites of cyanobacteria

Leanne A Pearson et al. Harmful Algae. 2016 Apr.

Abstract

The production of toxic metabolites by cyanobacterial blooms represents a significant threat to the health of humans and ecosystems worldwide. Here we summarize the current state of the knowledge regarding the genetics, biosynthesis and regulation of well-characterized cyanotoxins, including the microcystins, nodularin, cylindrospermopsin, saxitoxins and anatoxins, as well as the lesser-known marine toxins (e.g. lyngbyatoxin, aplysiatoxin, jamaicamides, barbamide, curacin, hectochlorin and apratoxins).

Keywords: Biosynthesis; Cyanobacteria; Cyanotoxins; Genetics; Regulation; Specialized metabolites.

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