A mouse monoclonal antibody to Vi antigen & its usefulness in the serotyping of Salmonella
- PMID: 2807427
Item in Clipboard
A mouse monoclonal antibody to Vi antigen & its usefulness in the serotyping of Salmonella
Indian J Med Res.
1989 Jul.
Abstract
Three IgM monoclonal antibodies (MoAb) designated as MK2, MK3 and MK5 and specific for the Vi antigen of Salmonella typhi have been produced. These antibodies recognise the epitope involving the O-acetyl group of Vi antigen. In slide agglutination tests, these MoAb's agglutinated all 11 isolates of S. typhi but not the other Gram negative bacteria. This selective reactivity makes them better reagents for the identification of S. typhi than the conventional polyclonal antiserum.
Similar articles
-
Production of Vi monoclonal antibodies and their application as diagnostic reagents.J Clin Microbiol. 1987 Mar;25(3):531-5. doi: 10.1128/jcm.25.3.531-535.1987. J Clin Microbiol. 1987. PMID: 3571457 Free PMC article.
-
Specificity of monoclonal antibodies binding to the polysaccharide antigens (Vi, O9) of Salmonella typhi.FEMS Microbiol Lett. 1992 Oct 1;76(1-2):173-8. doi: 10.1016/0378-1097(92)90382-x. FEMS Microbiol Lett. 1992. PMID: 1426999
-
Production of monoclonal antibodies to Vi polysaccharide antigen of Salmonella typhi.Asian Pac J Allergy Immunol. 1993 Jun;11(1):53-6. Asian Pac J Allergy Immunol. 1993. PMID: 8216560
-
The genome of Salmonella enterica serovar Typhi.Clin Infect Dis. 2007 Jul 15;45 Suppl 1:S29-33. doi: 10.1086/518143. Clin Infect Dis. 2007. PMID: 17582565 Review.
-
Serogroup and serotype classification of bacterial pathogens.Methods Enzymol. 1994;235:159-74. doi: 10.1016/0076-6879(94)35138-4. Methods Enzymol. 1994. PMID: 8057893 Review. No abstract available.