Enriching the Circadian Proteome
- PMID: 28076760
- DOI: 10.1016/j.cmet.2016.12.014
Enriching the Circadian Proteome
Abstract
Circadian clocks regulate most aspects of physiology and metabolism. Genome-wide approaches have uncovered widespread circadian rhythms in the transcriptome, cistrome, and epigenome of mice, and now two proteomics studies in this issue (Robles et al., 2016; Wang et al., 2016) reveal extensive circadian regulation of the nuclear and phosphoproteome.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver.Cell Metab. 2017 Jan 10;25(1):102-117. doi: 10.1016/j.cmet.2016.10.003. Epub 2016 Nov 3. Cell Metab. 2017. PMID: 27818260 Free PMC article.
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Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology.Cell Metab. 2017 Jan 10;25(1):118-127. doi: 10.1016/j.cmet.2016.10.004. Epub 2016 Nov 3. Cell Metab. 2017. PMID: 27818261
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