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Comment
. 2017 Jan 24;114(4):629-631.
doi: 10.1073/pnas.1619574114. Epub 2017 Jan 12.

Presenilin-1 mutations and Alzheimer's disease

Raymond J Kelleher 3rd  1   2 , Jie Shen  3   4
Affiliations
Comment

Presenilin-1 mutations and Alzheimer's disease

Raymond J Kelleher 3rd et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

J.S. is a member of the Scientific Advisory Board of Simcere Pharmaceutical Co.

Comment on

References

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    1. Duff K, et al. Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature. 1996;383(6602):710–713. - PubMed
    1. Scheuner D, et al. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer’s disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer’s disease. Nat Med. 1996;2(8):864–870. - PubMed

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