Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Nov-Dec;32(6):1354-1359.
doi: 10.12669/pjms.326.11199.

Can anemia predict perinatal outcomes in different stages of pregnancy?

Tayfun Vural  1 , Emrah Toz  2 , Aykut Ozcan  3 , Alper Biler  4 , Alper Ileri  5 , Abdurrahman Hamdi Inan  6
Affiliations

Can anemia predict perinatal outcomes in different stages of pregnancy?

Tayfun Vural et al. Pak J Med Sci. 2016 Nov-Dec.

Abstract

Objective: To investigate the effect of anemia on perinatal outcomes as preterm delivery (PTD) and low birth weight (LBW) in the different stages of pregnancy.

Methods: Medical records of 39,587 Turkish pregnant women who delivered between January 2011 and September 2014 were reviewed. Anemia during pregnancy was defined as hemoglobin (Hb)< 11 g/dl, low birth weight was defined as birth weight <2500 gr and PTD was defined as <37 weeks. The pregnant women were divided into three groups (Hb<10 gr/dl, Hb 10-11 gr/dl, Hb>11 gr/dl). Perinatal outcomes were compared between these anemic and non-anemic groups.

Results: The anemia prevalence in our study was 25.1%. In the first and second trimester of Hb<10g/dl group LBW ratio was significantly higher (respectively 13.5%, 9.8%, p=0.03; 22.7%, 14.7%, p=0.01). In the second and third trimesters of Hb<10 g/dl group PTD ratio was significantly higher (respectively 29.1%, 19%, p=0.00; 17.7%, 15.4% p=0.02). In the first trimester Hb<10 g/dl group cesarean section rate was significantly higher (respectively 65.2%, 57.6%, p = 0.01).

Conclusions: LBW infants and preterm birth rate was higher in Hb <10 gr/dl group than non-anemic in the first, second and third trimester. Hb <10 gr/dl group had higher cesarean rate in first trimester. The mean birth weight was significantly lower in anemic pregnant women in the second trimester. Preterm birth and cesarean section rate, in the group of anemic throughout pregnancy was higher than those of non-anemic in the whole pregnancy period.

Keywords: Anemia; Low birth weight; Preterm delivery.

PubMed Disclaimer

Conflict of interest statement

Declaration of interest: None.

References

    1. Diejomaeoh FM, Abdulaziz A, Adekile AD. Anemia in pregnancy. Int J Gynaecol Obstet. 1999;65:299–301. doi:10.1016/S0020-7292(99)00034-X. - PubMed
    1. United Nations. Administrative Committee on Coordination. Subcommittee on Nutrition. and International Food Policy Research Institute. Second report on the world nutrition situation: a report compiled from information available to the ACC/SCN.1992. Geneva, Switzerland Washington DC: United Nations International Food Policy Research Institute;
    1. Tzur T, Weintraub AY, Ruslan S, Eyal S. Can anemia in the first trimester predict obstetrical complications later in pregnancy? J Matern Fetal Neonatal Med. 2012;25:2454–2457. doi:10.3109/14767058.2012.703723. - PubMed
    1. Bondevik GT, Lie RT, Ulstein M, Kvale G. Maternal hematological status and risk of low birth weight and preterm delivery in Nepal. Acta Obstet Gynecol Scand. 2001;80:402–408. doi:10.1034/j.1600-0412.2001.d01-5.x. - PubMed
    1. Scanlon KS, Yip R, Schieve LA, Cogswell ME. High and low haemoglobin levels during pregnancy: differential risks for preterm birth and SGA. Obstet Gynecol. 2000;96:741–747. doi:10.1016/S0029-7844(00)00982-0. - PubMed

LinkOut - more resources