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Various methods exist to detect an astrovirus infection. Current methods include electron microscopy (EM), cell culture, immunoassays, polymerase chain reaction (PCR) and various other molecular approaches that can be applied in the context of diagnostic or in surveillance studies. With the advent of metagenomics, novel human astrovirus (HAstV) strains have been found in immunocompromised individuals in association with central nervous system (CNS) infections. This work reviews the past and current methods for astrovirus detection and their uses in both research laboratories and for medical diagnostic purposes.
Appleton H., Buckley M., Robertson M.H., Thom B.T. A search for faecal viruses in new-born and other infants. J. Hyg. (Lond.) 1978;81:279–283. doi: 10.1017/S0022172400025110.
-
DOI
-
PMC
-
PubMed
Kriston S., Willcocks M.M., Carter M.J., Cubitt W.D. Seroprevalence of astrovirus types 1 and 6 in London, determined using recombinant virus antigen. Epidemiol. Infect. 1996;117:159–164. doi: 10.1017/S0950268800001266.
-
DOI
-
PMC
-
PubMed
Koopmans M.P., Bijen M.H., Monroe S.S., Vinjé J. Age-stratified seroprevalence of neutralizing antibodies to astrovirus types 1 to 7 in humans in The Netherlands. Clin. Diagn. Lab. Immunol. 1998;5:33–37.
-
PMC
-
PubMed
Mitchell D.K., Matson D.O., Cubitt W.D., Jackson L.J., Willcocks M.M., Pickering L.K., Carter M.J. Prevalence of antibodies to astrovirus types 1 and 3 in children and adolescents in Norfolk, Virginia. Pediatr. Infect. Dis. J. 1999;18:249–254. doi: 10.1097/00006454-199903000-00008.
-
DOI
-
PubMed
Kobayashi S., Kobayashi M., Araki K., Shinozaki T., Yanagawa Y. [Antibody prevalence against astrovirus according to age groups] Kansenshogaku Zasshi. 1999;73:578–583. doi: 10.11150/kansenshogakuzasshi1970.73.578.
-
DOI
-
PubMed
