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. 2017 Jan 12;168(1-2):11-13.
doi: 10.1016/j.cell.2016.12.018. Epub 2017 Jan 12.

Shining a Light on Phase Separation in the Cell

Giulia Paci  1 , Edward A Lemke  2
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Free article

Shining a Light on Phase Separation in the Cell

Giulia Paci et al. Cell. .
Free article

Abstract

Phase separation of proteins is recognized as an important aspect of cellular organization and disease mechanisms. Shin et al. introduce a novel optogenetic tool, which enables different phase-space regimes inside living cells to be assessed and the transition paths between them to be studied with unprecedented spatiotemporal control.

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