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. 2017 Jan 14;25(1):1.
doi: 10.1186/s40199-017-0166-0.

Budget impact analysis of vaccination against Haemophilus influenzae type b as a part of a Pentavalent vaccine in the childhood immunization schedule of Iran

Fatemeh Teimouri  1 , Abbas Kebriaeezadeh  1   2 , Seyed Mohsen Zahraei  3 , MohammadMahdi Gheiratian  4 , Shekoufeh Nikfar  5   6
Affiliations

Budget impact analysis of vaccination against Haemophilus influenzae type b as a part of a Pentavalent vaccine in the childhood immunization schedule of Iran

Fatemeh Teimouri et al. Daru. .

Abstract

Background: Health decision makers need to know the impact of the development of a new intervention on the public health and health care costs so that they can plan for economic and financial objectives. The aim of this study was to determine the budget impact of adding Haemophilus influenzae type b (Hib) as a part of a Pentavalent vaccine (Hib-HBV-DTP) to the national childhood immunization schedule of Iran.

Methods: An excel-based model was developed to determine the costs of including the Pentavalent vaccine in the national immunization program (NIP), comparing the present schedule with the previous one (including separate DTP and hepatitis B vaccines). The total annual costs included the cost of vaccination (the vaccine and syringe) and the cost of Hib treatment. The health outcome was the estimated annual cases of the diseases. The net budget impact was the difference in the total annual cost between the two schedules. Uncertainty about the vaccine effectiveness, vaccination coverage, cost of the vaccine, and cost of the diseases were handled through scenario analysis.

Results: The total cost of vaccination during 5 years was $18,060,463 in the previous program and $67,774,786 in the present program. Inclusion of the Pentavalent vaccine would increase the vaccination cost about $49 million, but would save approximately $6 million in the healthcare costs due to reduction of disease cases and treatment costs. The introduction of the Pentavalent vaccine resulted in a net increase in the healthcare budget expenditure across all scenarios from $43.4 million to $50.7 million.

Conclusions: The results of this study showed that the inclusion of the Pentavalent vaccine in the NIP of Iran had a significant impact on the health care budget and increased the financial burden on the government. Budget impact of including Pentavalent vaccine in the national immunization schedule of Iranᅟ.

Keywords: Budget impact analysis; Haemophilus influenzae type b; Immunization schedule; Iran; Pentavalent vaccine.

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References

    1. Garattini L, Van de vooren K. Budget impact analysis in economic evaluation: a proposal for a clearer definition. Eur J Health Econ. 2011;12:499–502. doi: 10.1007/s10198-011-0348-5. - DOI - PubMed
    1. Sullivan SD, Mauskopf JA, Augustovski F, Caro JJ, Lee KM, Minchin M, et al. Budget Impact Analysis—Principles of Good Practice: Report of the ISPOR 2012 Budget Impact Analysis Good Practice II Task Force. Value Health. 2013;10(5):336–347. - PubMed
    1. Watt JP, Wolfson LJ, O’ Brien KL, Henkle E, Deloria-knoll M, McCall N, et al. Burden of disease caused by Hemophilus influenza type b in children younger than 5 years: global estimates. Lancet. 2009;374:903–911. doi: 10.1016/S0140-6736(09)61203-4. - DOI - PubMed
    1. Griffiths UK, Clark A, Hajjeh R. Cost effectiveness of Heamophilus influenzae type b conjugate vaccine in low and middle income countries: Regional analysis and assessment of major determinants. J Pediatr. 2013;163:S 50–S 59. doi: 10.1016/j.jpeds.2013.03.031. - DOI - PMC - PubMed
    1. Nisar MI, Jehan F, Shafig Y, Lassi ZS, Zaidi AKM. Conjugate vaccines for preventing Heamophilus influenzae type b infections in children under 5 years of age. Cochrane Database of Syst Rev. 2013, Issue 2. Art. No.: CD010377. doi:10.1002/14651858.CD010377.

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