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Editorial
. 2017 Jan 24;56(5):1164-1165.
doi: 10.1002/anie.201612143.

DNA-Encoded Compound Libraries as Open Source: A Powerful Pathway to New Drugs

Richard A Lerner  1 , Sydney Brenner  1
Affiliations
Editorial

DNA-Encoded Compound Libraries as Open Source: A Powerful Pathway to New Drugs

Richard A Lerner et al. Angew Chem Int Ed Engl. .

Abstract

"… We envisioned an iterative system where a unique DNA tag identifier that encoded the event was appended to each newly formed molecule. These vast collections of molecules are known today as DNA- encoded chemical libraries (DECLs), and allow scientists to do selections on the benchtop that previously required access to large and complex high-throughput screening centers …" Read more in the Guest Editorial by Richard A. Lerner and Sydney Brenner.

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