Recent progress in mild Csp3-H bond dehydrogenative or (mono-) oxidative functionalization

Abstract

Over the past few years, the development of oxidative methodologies towards efficient and selective direct Csp³-H bond functionalization processes has attracted tremendous attention from synthetic chemists. However, only a little attention has been given to the key role of the nature of the oxidant. This review aims at providing a brief summary of the recent advances in mild and more benign oxidative Csp³-H bond functionalization reactions, which are classified according to the type of oxidation system employed.