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Comment
. 2017 Jan 17;46(1):6-8.
doi: 10.1016/j.immuni.2017.01.001.

Fugue G Minor: Getting the Lymph Node Ensemble Together with Circadian Rhythm

Aaron Silva-Sanchez  1 , Troy D Randall  2
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Free article
Comment

Fugue G Minor: Getting the Lymph Node Ensemble Together with Circadian Rhythm

Aaron Silva-Sanchez et al. Immunity. .
Free article

Abstract

A fugue is characterized by the systematic repetition of a principal theme in simultaneous melodic lines. In this issue of Immunity, Druzd et al. (2017) show that a similar phenomenon occurs in lymph nodes (LNs), in which lymphocyte entry and exit is governed by repetitive circadian rhythms.

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  • Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses.
    Druzd D, Matveeva O, Ince L, Harrison U, He W, Schmal C, Herzel H, Tsang AH, Kawakami N, Leliavski A, Uhl O, Yao L, Sander LE, Chen CS, Kraus K, de Juan A, Hergenhan SM, Ehlers M, Koletzko B, Haas R, Solbach W, Oster H, Scheiermann C. Druzd D, et al. Immunity. 2017 Jan 17;46(1):120-132. doi: 10.1016/j.immuni.2016.12.011. Epub 2017 Jan 10. Immunity. 2017. PMID: 28087238 Free PMC article.

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