Th17 Cells Require You to Chew before You Swallow
- PMID: 28099867
- DOI: 10.1016/j.immuni.2016.12.016
Th17 Cells Require You to Chew before You Swallow
Abstract
How immunity is regulated at distinct epithelial tissues that vary in microbial occupancy and environmental and tissue specific cues isn't clear. Dutzan et al. (2017) report that mechanical-derived signals, not those from micro-organisms, are key to maintaining interleukin-17-expressing T helper (Th17) cells at the oral epithelia.
Copyright © 2017. Published by Elsevier Inc.
Comment on
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On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier.Immunity. 2017 Jan 17;46(1):133-147. doi: 10.1016/j.immuni.2016.12.010. Epub 2017 Jan 10. Immunity. 2017. PMID: 28087239 Free PMC article.
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