Mixed outcomes for computational predictions
- PMID: 28100399
- PMCID: PMC5245956
- DOI: 10.7554/eLife.22661
Mixed outcomes for computational predictions
Abstract
Experimental efforts to validate the output of a computational model that predicts new uses for existing drugs highlights the inherently complex nature of cancer biology.
Keywords: Reproducibility Project: Cancer Biology; cancer biology; cimetidine; drug retargeting; human; metascience; replication; reproducibility.
Conflict of interest statement
The author declares that no competing interests exist.
Comment on
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Replication Study: Discovery and preclinical validation of drug indications using compendia of public gene expression data.Elife. 2017 Jan 19;6:e17044. doi: 10.7554/eLife.17044. Elife. 2017. PMID: 28100397 Free PMC article.
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