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Review
. 2017 Feb;25(2):175-180.
doi: 10.1016/j.joca.2016.09.024. Epub 2017 Jan 16.

Osteoarthritis year in review 2016: biology

E N Blaney Davidson  1 , A P M van Caam  2 , P M van der Kraan  2
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Free article
Review

Osteoarthritis year in review 2016: biology

E N Blaney Davidson et al. Osteoarthritis Cartilage. 2017 Feb.
Free article

Abstract

This review highlights a selection of literature in the area of osteoarthritis biology published between the 2015 and 2016 Osteoarthritis Research Society International (OARSI) World Congress. Highlights were selected from a pubmed search covering cartilage, bone, inflammation and pain. A personal selection was made based, amongst other things, on topics presented during the 2015 conference. This covers circadian rhythm, TGF-β signaling, autophagy, SIRT6, exercise, lubricin, TLR's, pain and NGF. Furthermore, in this review we have made an effort to connect these seemingly distant topics into one scheme of connections between them, revealing a theoretical big picture underneath.

Keywords: Cartilage; Inflammation; Osteoarthritis; Subchondral bone.

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