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. 2017 Jan 6;6(1):41-44.
doi: 10.5527/wjn.v6.i1.41.

Hyponatremic hypertensive syndrome - a retrospective cohort study

Devdeep Mukherjee  1 , Rajiv Sinha  1 , Md Shakil Akhtar  1 , Agni Sekhar Saha  1
Affiliations

Hyponatremic hypertensive syndrome - a retrospective cohort study

Devdeep Mukherjee et al. World J Nephrol. .

Abstract

Aim: To ascertain the frequency of hyponatremic hypertensive syndrome (HHS) in a cohort of children with hypertensive emergency in a tertiary pediatric hospital.

Methods: A retrospective review was undertaken among children with hypertensive emergency admitted in our tertiary children hospital between June 2014 and December 2015 with an aim to identify any children with HHS. Three children with HHS were identified during this period.

Results: The 3 patients with HHS presented with hypertensive emergency. They were initially managed with Labetalol infusion and thereafter switched to oral anti-hypertensives (combination of Nifedipine sustained release, Hydralazine and Beta Blocker). All 3 were diagnosed to have unilateral renal artery stenosis. One child was lost to follow up, whereas the other 2 underwent renal angioplasty which was followed with normalization of blood pressure.

Conclusion: Despite activation of renin angiotensin axis secondary to renal artery stenosis, these groups of children have significant hyponatremia. Renal re-vascularisation produces excellent results in most of them.

Keywords: Encephalopathy; Hypertension; Hyponatremia; Paediatric; Renovascular.

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Conflict of interest statement

Conflict-of-interest statement: The authors declare no conflicts of interest regarding this manuscript.

Figures

Figure 1
Figure 1
The angiography of three cases. A: CT angiography shows narrowing of left renal artery with duplication of artery. Small left kidney with compensatory hypertrophy of right kidney; B: MRI brain shows posterior reversible encephalopathy syndrome; C: Digital subtraction angiography shows stenosed left renal artery. MRI: Magnetic resonance imaging; CT: Computed tomography.
See this image and copyright information in PMC

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