Resisting the Urge to Act: DREADDs Modifying Habits
- PMID: 28104285
- PMCID: PMC5285454
- DOI: 10.1016/j.tins.2016.12.002
Resisting the Urge to Act: DREADDs Modifying Habits
Erratum in
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Resisting the Urge to Act: DREADDS Modifying Habits: (Trends in Neurosciences 40, 61-62; 2017).Trends Neurosci. 2017 May;40(5):324. doi: 10.1016/j.tins.2017.03.007. Epub 2017 Apr 13. Trends Neurosci. 2017. PMID: 28413092 No abstract available.
Abstract
Recently, Meyer and Bucci used chemogenetic technology - artificial excitatory and inhibitory receptors - to modulate neuronal activity in two connected brain regions in opposite directions simultaneously. This innovative manipulation revealed that the two regions studied, orbitofrontal cortex and nucleus accumbens, are not sequentially dependent during contextual decision-making.
Published by Elsevier Ltd.
Comment on
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Imbalanced Activity in the Orbitofrontal Cortex and Nucleus Accumbens Impairs Behavioral Inhibition.Curr Biol. 2016 Oct 24;26(20):2834-2839. doi: 10.1016/j.cub.2016.08.034. Epub 2016 Sep 29. Curr Biol. 2016. PMID: 27693139 Free PMC article.
References
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- Kamin LJ. Predictability, surprise, attention and conditioning. In: Church BACRM, editor. Punishment and aversive behavior. Appleton-Century-Crofts; 1969. pp. 279–296.
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