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Editorial
. 2017 Jan 20;120(2):249-251.
doi: 10.1161/CIRCRESAHA.116.310339.

Hypertension Opens the Flood Gates to the Gut Microbiota

W Robert Taylor  1 , Kiyoko Takemiya  2
Affiliations
Editorial

Hypertension Opens the Flood Gates to the Gut Microbiota

W Robert Taylor et al. Circ Res. .
No abstract available

Keywords: Editorials; dysbiosis; hypertension; inflammation; microbiome; sympathetic nervous system.

PubMed Disclaimer

Conflict of interest statement

Statement Kiyoko Takemiya has no relevant conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Overview of the impact of the impact of sympathetic nerve stimulation on gut permeability and hypertension.
See this image and copyright information in PMC

Comment on

  • Hypertension-Linked Pathophysiological Alterations in the Gut.
    Santisteban MM, Qi Y, Zubcevic J, Kim S, Yang T, Shenoy V, Cole-Jeffrey CT, Lobaton GO, Stewart DC, Rubiano A, Simmons CS, Garcia-Pereira F, Johnson RD, Pepine CJ, Raizada MK. Santisteban MM, et al. Circ Res. 2017 Jan 20;120(2):312-323. doi: 10.1161/CIRCRESAHA.116.309006. Epub 2016 Oct 31. Circ Res. 2017. PMID: 27799253 Free PMC article.

References

    1. Koeth RA, Wang Z, Levison BS, Buffa JA, Org E, Sheehy BT, Britt EB, Fu X, Wu Y, Li L, Smith JD, DiDonato JA, Chen J, Li H, Wu GD, Lewis JD, Warrier M, Brown JM, Krauss RM, Tang WH, Bushman FD, Lusis AJ, Hazen SL. Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med. 2013;19:576–585. - PMC - PubMed
    1. Santisteban MM, Qi Y, Zubcevic J, Kim S, Yang T, Shenoy V, Cole-Jeffrey CT, Lobaton GO, Stewart DC, Rubiano A, Simmons CS, Garcia-Pereira F, Johnson RD, Pepine CJ, Raizada MK. Hypertension-Linked Pathophysiological Alterations in the Gut. Circ Res. 2016 - PMC - PubMed
    1. Afsar B, Vaziri ND, Aslan G, Tarim K, Kanbay M. Gut hormones and gut microbiota: implications for kidney function and hypertension. J Am Soc Hypertens. 2016;10:954–961. - PubMed
    1. Ohri SK, Somasundaram S, Koak Y, Macpherson A, Keogh BE, Taylor KM, Menzies IS, Bjarnason I. The effect of intestinal hypoperfusion on intestinal absorption and permeability during cardiopulmonary bypass. Gastroenterology. 1994;106:318–323. - PubMed
    1. Leclercq S, Matamoros S, Cani PD, Neyrinck AM, Jamar F, Starkel P, Windey K, Tremaroli V, Backhed F, Verbeke K, de Timary P, Delzenne NM. Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity. Proc Natl Acad Sci U S A. 2014;111:E4485–E4493. - PMC - PubMed