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Comment
. 2017 Mar;7(3):238.
doi: 10.1158/2159-8290.CD-NB2017-006. Epub 2017 Jan 19.

Not All Esophageal Tumors Equal

No authors listed
Comment

Not All Esophageal Tumors Equal

No authors listed. Cancer Discov. 2017 Mar.

Abstract

Although squamous cell carcinomas and adenocarcinomas of the esophagus differ histologically, they are often lumped together in clinical trials. Genomic analysis shows that the two cancers are molecularly distinct. Esophageal adenocarcinomas are more similar to stomach adenocarcinomas, whereas esophageal squamous cell carcinomas are closer to head and neck squamous cell carcinomas.

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  • Integrated genomic characterization of oesophageal carcinoma.
    Cancer Genome Atlas Research Network; Analysis Working Group: Asan University; BC Cancer Agency; Brigham and Women’s Hospital; Broad Institute; Brown University; Case Western Reserve University; Dana-Farber Cancer Institute; Duke University; Greater Poland Cancer Centre; Harvard Medical School; Institute for Systems Biology; KU Leuven; Mayo Clinic; Memorial Sloan Kettering Cancer Center; National Cancer Institute; Nationwide Children’s Hospital; Stanford University; University of Alabama; University of Michigan; University of North Carolina; University of Pittsburgh; University of Rochester; University of Southern California; University of Texas MD Anderson Cancer Center; University of Washington; Van Andel Research Institute; Vanderbilt University; Washington University; Genome Sequencing Center: Broad Institute; Washington University in St. Louis; Genome Characterization Centers: BC Cancer Agency; Broad Institute; Harvard Medical School; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University; University of North Carolina; University of Southern California Epigenome Center; University of Texas MD Anderson Cancer Center; Van Andel Research Institute; Genome Data Ana… See abstract for full author list ➔ Cancer Genome Atlas Research Network, et al. Nature. 2017 Jan 12;541(7636):169-175. doi: 10.1038/nature20805. Epub 2017 Jan 4. Nature. 2017. PMID: 28052061 Free PMC article.

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