. 2017 May;31(5):1226-1229.

doi: 10.1038/leu.2017.28. Epub 2017 Jan 20.

Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes

L Guidugli¹, A K Johnson¹, G Alkorta-Aranburu¹, V Nelakuditi¹, K Arndt¹, J E Churpek², L A Godley², D Townsley³, N S Young³, C Fitzpatrick⁴, D Del Gaudio¹, S Das¹, Z Li¹

Affiliations

¹ Department of Human Genetics, The University of Chicago, Chicago, IL, USA.
² Department of Medicine, Comprehensive Cancer Center and Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.
³ Hematology Branch, Cell Biology Section, National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD, USA.
⁴ Department of Pathology, The University of Chicago, Chicago, IL, USA.

PMID: 28104920
PMCID: PMC5420790
DOI: 10.1038/leu.2017.28

Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes

L Guidugli et al. Leukemia. 2017 May.

. 2017 May;31(5):1226-1229.

doi: 10.1038/leu.2017.28. Epub 2017 Jan 20.

Authors

L Guidugli¹, A K Johnson¹, G Alkorta-Aranburu¹, V Nelakuditi¹, K Arndt¹, J E Churpek², L A Godley², D Townsley³, N S Young³, C Fitzpatrick⁴, D Del Gaudio¹, S Das¹, Z Li¹

Affiliations

¹ Department of Human Genetics, The University of Chicago, Chicago, IL, USA.
² Department of Medicine, Comprehensive Cancer Center and Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA.
³ Hematology Branch, Cell Biology Section, National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD, USA.
⁴ Department of Pathology, The University of Chicago, Chicago, IL, USA.

PMID: 28104920
PMCID: PMC5420790
DOI: 10.1038/leu.2017.28

No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

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References

1. Churpek JE, Lorenz R, Nedumgottil S, Onel K, Olopade OI, Sorrell A et al. Proposal for the clinical detection and management of patients and their family members with familial myelodysplastic syndrome/acute leukemia predisposition syndromes. Leuk Lymphoma 2013; 54: 28–35. - PubMed
1. Bannon SA, DiNardo CD. Hereditary predispositions to myelodysplastic syndrome. Int J Mol Sci 2016; 17: 1–11. - PMC - PubMed
1. Babushok DV, Bessler M, Olson TS. Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults. Leuk Lymphoma 2016; 57: 520–536. - PMC - PubMed
1. Owen C, Barnett M, Fitzgibbon J. Familial myelodysplasia and acute myeloid leukaemia—a review. Br J Haematol 2008; 140: 123–132. - PubMed
1. Babushok DV, Bessler M. Genetic predisposition syndromes: when should they be considered in the work-up of MDS? Best Pract Res Clin Haematol 2015; 28: 55–68. - PMC - PubMed

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Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes

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Clinical utility of gene panel-based testing for hereditary myelodysplastic syndrome/acute leukemia predisposition syndromes

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