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. 2017 Apr 24;23(23):5410-5413.
doi: 10.1002/chem.201605218. Epub 2017 Feb 27.

Improved and General Manganese-Catalyzed N-Methylation of Aromatic Amines Using Methanol

Jacob Neumann  1 , Saravanakumar Elangovan  1   2 , Anke Spannenberg  1 , Kathrin Junge  1 , Matthias Beller  1
Affiliations

Improved and General Manganese-Catalyzed N-Methylation of Aromatic Amines Using Methanol

Jacob Neumann et al. Chemistry. .

Abstract

A novel lutidine-based manganese PNP-pincer complex has been synthesized for the selective N-methylation of aromatic amines with methanol. Using borrowing hydrogen methodology, a selection of differently functionalized aniline derivatives is selectively methylated in good yields.

Keywords: amines; borrowing hydrogen; manganese; methylation; pincer complex.

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