[Accelerated fractionation in malignant gliomas]

Abstract

Recent radiobiological data have indicated that shortening of the overall treatment time could improve the therapeutic ratio of the radiotherapy on malignant gliomas. Twenty-five inoperable or recurrent malignant gliomas were treated with accelerated fractionation, two sessions per day, 1.5-2 Gy per fraction. This regimen was well tolerated by all the patients and the local response was excellent. To attain the local control, however, other effective modality should be combined.