An official website of the United States government
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before
sharing sensitive information, make sure you’re on a federal
government site.
The site is secure.
The https:// ensures that you are connecting to the
official website and that any information you provide is encrypted
and transmitted securely.
1 Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, 01307 Dresden, Germany.
2 Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, 01307 Dresden, Germany andreas.linkermann@uniklinikum-dresden.de.
1 Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, 01307 Dresden, Germany.
2 Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technische Universität Dresden, 01307 Dresden, Germany andreas.linkermann@uniklinikum-dresden.de.
In recent years, our knowledge of how cells die by regulated pathways of necrosis has increased tremendously. In this issue, Distéfano et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605110) provide yet another milestone in our understanding of regulated necrosis as they identify a ferroptosis-like cell death in Arabidopsis thaliana.
Ding J., Wang K., Liu W., She Y., Sun Q., Shi J., Sun H., Wang D.C., and Shao F.. 2016. Pore-forming activity and structural autoinhibition of the gasdermin family. Nature. 535:111–116. 10.1038/nature18590
-
DOI
-
PubMed
Distéfano A.M., Martin M.V., Córdoba J.P., Bellido A.M., D’Ippólito S., Colman S.L., Soto D., Roldan J.A., Bartoli C.G., Zabaleta E.J., et al. . 2017. Heat stress induces ferroptosis-like cell death in plants. J. Cell Biol. 10.1083/jcb.201605110
-
DOI
-
PMC
-
PubMed
Dixon S.J., Lemberg K.M., Lamprecht M.R., Skouta R., Zaitsev E.M., Gleason C.E., Patel D.N., Bauer A.J., Cantley A.M., Yang W.S., et al. . 2012. Ferroptosis: An iron-dependent form of nonapoptotic cell death. Cell. 149:1060–1072. 10.1016/j.cell.2012.03.042
-
DOI
-
PMC
-
PubMed
Huysmans M., Lema A S., Coll N.S., and Nowack M.K.. 2017. Dying two deaths — programmed cell death regulation in development and disease. Curr. Opin. Plant Biol. 35:37–44. 10.1016/j.pbi.2016.11.005
-
DOI
-
PubMed
Kaiser W.J., Upton J.W., and Mocarski E.S.. 2013. Viral modulation of programmed necrosis. Curr. Opin. Virol. 3:296–306. 10.1016/j.coviro.2013.05.019
-
DOI
-
PMC
-
PubMed