Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Mar;6(3):153-155.
doi: 10.1002/psp4.12173.

Implementing Genomic Clinical Decision Support for Drug-Based Precision Medicine

R R Freimuth  1 , C M Formea  2 , J M Hoffman  3 , E Matey  2 , J F Peterson  4 , R D Boyce  5
Affiliations
Review

Implementing Genomic Clinical Decision Support for Drug-Based Precision Medicine

R R Freimuth et al. CPT Pharmacometrics Syst Pharmacol. 2017 Mar.

Abstract

The explosive growth of patient-specific genomic information relevant to drug therapy will continue to be a defining characteristic of biomedical research. To implement drug-based personalized medicine (PM) for patients, clinicians need actionable information incorporated into electronic health records (EHRs). New clinical decision support (CDS) methods and informatics infrastructure are required in order to comprehensively integrate, interpret, deliver, and apply the full range of genomic data for each patient.

PubMed Disclaimer

References

    1. Masys, D.R. et al Technical desiderata for the integration of genomic data into Electronic Health Records. J. Biomed. Inform. 45, 419–422 (2012). - PMC - PubMed
    1. AHRQ . Section 2: Overview of CDS Five Rights. <https://healthit.ahrq.gov/ahrq-funded-projects/clinical-decision-support.... Accessed 1 December 2016.
    1. Caudle, K.E. et al Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process. Curr. Drug Metab. 15, 209–217 (2014). - PMC - PubMed
    1. Hoffman, J.M. et al Developing knowledge resources to support precision medicine: principles from the Clinical Pharmacogenetics Implementation Consortium (CPIC). J. Am. Med. Inform. Assoc. 23, 796–801 (2016). - PMC - PubMed
    1. Welch, B.M. , Eilbeck, K. , Del Fiol, G. , Meyer, L.J. & Kawamoto, K. Technical desiderata for the integration of genomic data with clinical decision support. J. Biomed. Inform. 51, 3–7 (2014). - PubMed

MeSH terms

LinkOut - more resources