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Editorial
. 2017 Jan 23;6(1):e005459.
doi: 10.1161/JAHA.116.005459.

Iron and Sex Cross Paths in the Heart

Jason S Shapiro  1 , Hsiang-Chun Chang  1 , Hossein Ardehali  2
Affiliations
Editorial

Iron and Sex Cross Paths in the Heart

Jason S Shapiro et al. J Am Heart Assoc. .
No abstract available

Keywords: Editorials; heart; iron; sex.

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Figures

Figure 1
Figure 1
Key effects of sex on the response to iron overload in the murine heart. Male and female mice accumulate roughly equal amounts of cardiac iron in response to iron overload. Female mice express greater levels of ferritin and antioxidant proteins, resulting in reduced reactive oxygen species (ROS) production and preserved cardiac function.
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