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. 2017 Jan 17;5(1):3-7.
doi: 10.1002/mgg3.272. eCollection 2017 Jan.

Genetics and genomics etiology of nonsyndromic orofacial clefts

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Genetics and genomics etiology of nonsyndromic orofacial clefts

Wasiu L Adeyemo et al. Mol Genet Genomic Med. .

Abstract

Orofacial clefts (OFC) are complex birth defects. Studies using contemporary genomic techniques, bioinformatics, and statistical analyses have led to appreciable advances in identifying the causes of syndromic forms of clefts. This commentary gives an overview of the important cleft gene discoveries found using various genomic methods and tools.

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