Genetics and genomics etiology of nonsyndromic orofacial clefts
- PMID: 28116324
- PMCID: PMC5241211
- DOI: 10.1002/mgg3.272
Genetics and genomics etiology of nonsyndromic orofacial clefts
Abstract
Orofacial clefts (OFC) are complex birth defects. Studies using contemporary genomic techniques, bioinformatics, and statistical analyses have led to appreciable advances in identifying the causes of syndromic forms of clefts. This commentary gives an overview of the important cleft gene discoveries found using various genomic methods and tools.
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