[Acquisition of the sequence of a new subclass of human alpha- satellite DNA, localized in the centromere regions of two pairs of acrocentric chromosomes]
[Article in
Russian]
- PMID: 2811898
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[Acquisition of the sequence of a new subclass of human alpha- satellite DNA, localized in the centromere regions of two pairs of acrocentric chromosomes]
[Article in
Russian]
Mol Gen Mikrobiol Virusol.
1989 Jun.
Abstract
The results are presented in the paper on obtaining of a clone of sub-group of alpha-satellite human DNA localized in heterochromatin regions of two pairs of acrocentric chromosomes. The obtained repeated DNA sequence is represented in a genome by some 20,000 copies. Using of the blot-hybridization method made it possible to show the polymorphic restriction variant distribution being preserved in different individuals genomes. Intergenomic structural heterogeneity in this alpha-satellite DNA sub-group has been found only by using restriction endonuclease BamHI.
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