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Case Reports
. 2017 Jan 25:2017:bcr2016217774.
doi: 10.1136/bcr-2016-217774.

Interesting association of neurofibroma with diffuse cystic lung disease (NF-DLD)

Sharath P Madhyastha  1 , Vinaya Gopalaswamy  1 , Charan Thej Reddy  1 , Raviraja V Acharya  1
Affiliations
Case Reports

Interesting association of neurofibroma with diffuse cystic lung disease (NF-DLD)

Sharath P Madhyastha et al. BMJ Case Rep. .
No abstract available

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Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Figure 1
Figure 1
MRI of the spinal cord, sagittal view, (A) T2-weighted, (B) T1-weighted, showing benign intraspinal extradural dumb-bell-shaped neurogenic tumour measuring 3.8×2.0×3.0 cm at the D6–7 level (arrow) causing significant spinal cord compression.
Figure 2
Figure 2
Coronal (A) and axial (B) images of MRI spinal cord showing neurofibroma (dumb-bell-shaped) at the D6 level (arrow) causing significant compression and rightward displacement of the spinal cord.
Figure 3
Figure 3
Chest radiograph showing cystic bronchiectatic changes (arrows) in both lower zones.
Figure 4
Figure 4
Coronal (A) and axial (B) images of CT chest showing cystic bronchiectatic changes in bilateral lower lobes, apical and posterior segments of the right upper lobe and posterior segment of the left upper lobe.
Figure 5
Figure 5
Postoperative, frontal (A) and lateral (B) radiograph of the chest with spinal fixative device is seen at the D4–7 level (transpedicular stabilisation).
Figure 6
Figure 6
Histopathology of the excised tumour at low power (A) and high power (B) showing interlacing bundles of spindle-shaped cells, having elongated wavy nuclei and eosinophilic cytoplasmic process, fibroblasts, proliferating capillaries.
See this image and copyright information in PMC

References

    1. Davies PBD. Diffuse pulmonary involvement in von Recklinhausen's disease: a new syndrome. Thorax 1963;18:198.
    1. Zamora A, Collard H, Wolters P et al. . Neurofibromatosis-associated lung disease: a case series and literature review. Eur Respir J 2006;29:210–14. - PubMed

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