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Review
. 2016 Dec 3;16(12):e41564.
doi: 10.5812/hepatmon.41564. eCollection 2016 Dec.

Liver Illness and Psychiatric Patients

Paul Carrier  1 , Marilyne Debette-Gratien  1 , Murielle Girard  2 , Jérémie Jacques  3 , Philippe Nubukpo  4 , Véronique Loustaud-Ratti  1
Affiliations
Review

Liver Illness and Psychiatric Patients

Paul Carrier et al. Hepat Mon. .

Abstract

Patients with psychiatric disorders are usually more exposed to multiple somatic illnesses, including liver diseases. Specific links are established between psychiatric disorders and alcohol hepatitis, hepatitis B, and hepatitis C in the population as a whole, and specifically in drug abusers. Metabolic syndrome criteria, and associated steatosis or non-alcoholic steato-hepatitis (NASH) are frequent in patients with chronic psychiatric disorders under psychotropic drugs, and should be screened. Some psychiatric medications, such as neuroleptics, mood stabilizers, and a few antidepressants, are often associated with drug-induced liver injury (DILI). In patients with advanced chronic liver diseases, the prescription of some specific psychiatric treatments should be avoided. Psychiatric disorders can be a limiting factor in the decision-making and following up for liver transplantation.

Keywords: Hepatotoxicity; Mental Disorders; Non-Alcoholic Fatty Liver Disease; Viral Hepatitis.

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