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. 2016 Jul-Sep;9(3):255-260.
doi: 10.1016/j.slsci.2016.11.004. Epub 2016 Nov 30.

Does abstinence resolve poor sleep quality in former methamphetamine dependents?

Amir Rezaei Ardani  1 , Seyyed Ali Saghebi  1 , Mahsa Nahidi  1 , Farzaneh Zeynalian  1
Affiliations

Does abstinence resolve poor sleep quality in former methamphetamine dependents?

Amir Rezaei Ardani et al. Sleep Sci. 2016 Jul-Sep.

Abstract

Background and objective: Among substances that have a significant effect on sleep are stimulants, including amphetamines. As there are few studies assessing sleep quality in methamphetamine withdrawal this study aims to evaluate changes in sleep quality of methamphetamine dependent patients during early remission period by controlling depression and anxiety as confounding variables.

Methods: This study was conducted in Mashhad, Iran. Ninety amphetamine dependent patients, who were admitted in residential centers during 2012-2014 and met our inclusion criteria, were chosen by purposive nonprobability sampling method. Sleep quality was assessed by Pittsburg sleep questionnaire, in the first, second, and after the fourth week of abstinence. Additionally all participants were assessed by Beck Depression Inventory-2 and Beck Anxiety Inventory for controlling depressive and anxiety symptoms.

Results: The prevalence of improper quality of sleep was very high (97.8%) within the first week of withdrawal, but it reduced considerably four weeks after abstinence (52.2%), which was statistically significant (P=0.00). The variations of depression and anxiety levels within four weeks after quitting methamphetamine, have low impact on variation of patients' sleep quality (adjusted R2<0.5). Furthermore, the effectiveness of these two intervening variables on patients' quality of sleep was dwindled over time after abstinence.

Conclusions: This study showed that the patients' quality of sleep improved significantly four weeks after abstinence and its variation was independent from variations in anxiety and depressive symptoms.

Keywords: Abstinence; Amphetamine; Anxiety; Depression; Sleep quality.

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Figures

Fig. 1
Fig. 1
Pattern of frequency distribution for the sleep quality of participants at days 1–3 of the study (first assessment).
Fig. 2
Fig. 2
Pattern of frequency distribution for the sleep quality of participants at days 11–14 of the study (second assessment).
Fig. 3
Fig. 3
Pattern of frequency distribution for the sleep quality of participants at days 28–35 of the study (third assessment).
See this image and copyright information in PMC

References

    1. Hasler G., Buysse D.J., Gamma A., Ajdacic V., Eich D., Rossler W. Excessive daytime sleepiness in young adults: a 20-year prospective community study. J Clin Psychiatry. 2005;66(4):521–529. - PubMed
    1. Ozminkowski R.J., Wang S., Walsh J.K. The direct and indirect costs of untreated insomnia in adults in the United States. Sleep. 2007;30(3):263–273. - PubMed
    1. Yi H., Shin K., Shin C. Development of the sleep quality scale. J Sleep Res. 2006;15(3):309–316. - PubMed
    1. Leger D., Guilleminault C., Bader G., Levy E., Paillard M. Medical and socio-professional impact of insomnia. Sleep. 2002;25(6):625–629. - PubMed
    1. Morin C.M., Daley M., Ouellet M.C. Insomnia in adults. Curr Treat Options Neurol. 2001;3(1):9–18. - PubMed