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. 2017 Jan 17:11:98-102.
doi: 10.1016/j.dib.2017.01.008. eCollection 2017 Apr.

Data on gut metagenomes of the patients with alcoholic dependence syndrome and alcoholic liver cirrhosis

Alexander V Tyakht  1 , Veronika B Dubinkina  1 , Vera Y Odintsova  2 , Konstantin S Yarygin  3 , Boris A Kovarsky  2 , Alexander V Pavlenko  3 , Dmitry S Ischenko  3 , Anna S Popenko  2 , Dmitry G Alexeev  3 , Anastasiya Y Taraskina  4 , Regina F Nasyrova  4 , Evgeny M Krupitski  4 , Nino V Shalikiani  5 , Igor G Bakulin  5 , Petr L Shcherbakov  5 , Lyubov O Skorodumova  2 , Andrei K Larin  2 , Elena S Kostryukova  3 , Rustam A Abdulkhakov  6 , Sayar R Abdulkhakov  7 , Sergey Y Malanin  8 , Ruzilya K Ismagilova  8 , Tatiana V Grigoryeva  8 , Elena N Ilina  2 , Vadim M Govorun  1
Affiliations

Data on gut metagenomes of the patients with alcoholic dependence syndrome and alcoholic liver cirrhosis

Alexander V Tyakht et al. Data Brief. .

Abstract

Alcoholism is associated with significant changes in gut microbiota composition. Metagenomic sequencing allows to assess the altered abundance levels of bacterial taxa and genes in a culture-independent way. We collected 99 stool samples from the patients with alcoholic dependence syndrome (n=72) and alcoholic liver cirrhosis (n=27). Each of the samples was surveyed using "shotgun" (whole-genome) sequencing on SOLiD platform. The reads are deposited in the ENA (project ID: PRJEB18041).

Keywords: Alcohol dependence syndrome; Alcoholic liver cirrhosis; Alcoholism; Dysbiosis; Gut microbiota; Metagenome; “Shotgun” metagenomics.

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References

    1. Tyakht A.V., Kostryukova E.S., Popenko A.S., Belenikin M.S., Pavlenko A.V., Larin A.K., Karpova I.Y., Selezneva O.V., Semashko T.A., Ospanova E.A., Babenko V.V., Maev I.V., Cheremushkin S.V., Kucheryavyy Y.A., Shcherbakov P.L., Grinevich V.B., Efimov O.I., Sas E.I., Abdulkhakov R.A., Abdulkhakov S.R., Lyalyukova E.A., Livzan M.A., Vlassov V.V., Sagdeev R.Z., Tsukanov V.V., Osipenko M.F., Kozlova I.V., Tkachev A.V., Sergienko V.I., Alexeev D.G., Govorun V.M. Human gut microbiota community structures in urban and rural populations in Russia. Nat. Commun. 2013;4:2469. - PMC - PubMed

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