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Editorial
. 2017 Feb 2;12(1):36.
doi: 10.1186/s13014-017-0764-5.

Intraoperative irradiation: precision medicine for quality cancer control promotion

Felipe A Calvo  1   2   3
Affiliations
Editorial

Intraoperative irradiation: precision medicine for quality cancer control promotion

Felipe A Calvo. Radiat Oncol. .

Abstract

Intraoperative irradiation was implemented 4 decades ago, pioneering the efforts to improve precision in local cancer therapy by combining real-time surgical exploration/resection with high single dose radiotherapy (Gunderson et al., Intraoperative irradiation: techniques and results, 2011). Clinical and technical developments have led to very precise radiation dose deposit. The ability to deliver a very precise dose of radiation is an essential element of contemporary multidisciplinary individualized oncology.This issue of Radiation Oncology contains a collection of expert review articles and updates with relevant data regarding intraoperative radiotherapy. Technology, physics, biology of single dose and clinical results in a variety of cancer sites and histologies are described and analyzed. The state of the art for advanced cancer care through medical innovation opens a significant opportunity for individualize cancer management across a broad spectrum of clinical practice. The advantage for tailoring diagnostic and treatment decisions in an individualized fashion will translate into precise medical treatment.

Keywords: High single dose radiotherapy; Intraoperative irradiation; Precision medicine; Real-time surgical exploration.

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