The tip of the thrombos-is-berg

Affiliations

Comment

Monica L Hulbert. Sci Transl Med. 2017.

. 2017 Feb 1;9(375):eaam6053.

doi: 10.1126/scitranslmed.aam6053. Epub 2017 Feb 1.

¹ Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA. Email: hulbert_m@kids.wustl.edu.

Abstract

A high risk of venous thromboembolic events is just one of the challenges faced by people with malignant brain tumors.

Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism.
Riedl J, Preusser M, Nazari PM, Posch F, Panzer S, Marosi C, Birner P, Thaler J, Brostjan C, Lötsch D, Berger W, Hainfellner JA, Pabinger I, Ay C. Riedl J, et al. Blood. 2017 Mar 30;129(13):1831-1839. doi: 10.1182/blood-2016-06-720714. Epub 2017 Jan 10. Blood. 2017. PMID: 28073783 Free PMC article.