What is the role of empirical treatment for suspected invasive candidiasis in non-neutropenic non transplanted patients in the intensive care unit?-Empiricus strikes back!

Affiliations

¹ CHU Nantes, PHU3, Medical Intensive Care Unit, place A. Ricordeau, Nantes, F-44093, France; ; Nantes University, UPRES EA 3826, Laboratory of clinical and experimental therapeutics of infections, IRS2-Nantes Biotech, F-44200, France.
² CHU Nantes, PHU3, General Surgical Intensive Care Unit, Anesthesiology Department, Laënnec Hospital, place A. Ricordeau, Nantes, F-44093, France.
³ CHU Nantes, PHU3, Cardiac Surgery Intensive Care Unit, Anesthesiology Department, Laënnec Hospital, place A. Ricordeau, Nantes, F-44093, France.
⁴ Nantes University, UPRES EA 3826, Laboratory of clinical and experimental therapeutics of infections, IRS2-Nantes Biotech, F-44200, France; ; CHU Nantes, PHU3, Infectious Diseases, place A. Ricordeau, Nantes, F-44093, France.
⁵ CHU Nantes, PHU7, Laboratory of Parasitology and Medical Mycologie, Nantes, F-44093, France; ; Parasitology and Medical Mycology Department, Nantes University, Nantes Atlantique University, EA1155-IICiMed, IRS2-Nantes Biotech, Nantes, F-44200, France.

Editorial

Cédric Bretonnière et al. J Thorac Dis. 2016 Dec.

. 2016 Dec;8(12):E1719-E1722.

doi: 10.21037/jtd.2016.12.99.

¹ CHU Nantes, PHU3, Medical Intensive Care Unit, place A. Ricordeau, Nantes, F-44093, France; ; Nantes University, UPRES EA 3826, Laboratory of clinical and experimental therapeutics of infections, IRS2-Nantes Biotech, F-44200, France.
² CHU Nantes, PHU3, General Surgical Intensive Care Unit, Anesthesiology Department, Laënnec Hospital, place A. Ricordeau, Nantes, F-44093, France.
³ CHU Nantes, PHU3, Cardiac Surgery Intensive Care Unit, Anesthesiology Department, Laënnec Hospital, place A. Ricordeau, Nantes, F-44093, France.
⁴ Nantes University, UPRES EA 3826, Laboratory of clinical and experimental therapeutics of infections, IRS2-Nantes Biotech, F-44200, France; ; CHU Nantes, PHU3, Infectious Diseases, place A. Ricordeau, Nantes, F-44093, France.
⁵ CHU Nantes, PHU7, Laboratory of Parasitology and Medical Mycologie, Nantes, F-44093, France; ; Parasitology and Medical Mycology Department, Nantes University, Nantes Atlantique University, EA1155-IICiMed, IRS2-Nantes Biotech, Nantes, F-44200, France.

No abstract available

Conflict of interest statement

The authors have no conflicts of interest to declare.

Empirical Micafungin Treatment and Survival Without Invasive Fungal Infection in Adults With ICU-Acquired Sepsis, Candida Colonization, and Multiple Organ Failure: The EMPIRICUS Randomized Clinical Trial.
Timsit JF, Azoulay E, Schwebel C, Charles PE, Cornet M, Souweine B, Klouche K, Jaber S, Trouillet JL, Bruneel F, Argaud L, Cousson J, Meziani F, Gruson D, Paris A, Darmon M, Garrouste-Orgeas M, Navellou JC, Foucrier A, Allaouchiche B, Das V, Gangneux JP, Ruckly S, Maubon D, Jullien V, Wolff M; EMPIRICUS Trial Group. Timsit JF, et al. JAMA. 2016 Oct 18;316(15):1555-1564. doi: 10.1001/jama.2016.14655. JAMA. 2016. PMID: 27706483 Clinical Trial.

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