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. 2018 Apr;22(4):1075-1079.
doi: 10.1007/s10461-017-1701-1.

Behavioral Changes Following Uptake of HIV Pre-exposure Prophylaxis Among Men Who Have Sex with Men in a Clinical Setting

Catherine E Oldenburg  1 , Amy S Nunn  2 , Madeline Montgomery  3 , Alexi Almonte  3 , Leandro Mena  4 , Rupa R Patel  5 , Kenneth H Mayer  6   7 , Philip A Chan  8   9
Affiliations

Behavioral Changes Following Uptake of HIV Pre-exposure Prophylaxis Among Men Who Have Sex with Men in a Clinical Setting

Catherine E Oldenburg et al. AIDS Behav. 2018 Apr.

Abstract

We describe changes in sexual behaviors among men who have sex with men (MSM) following initiation of pre-exposure prophylaxis (PrEP) in a clinic-based sample of MSM initiating PrEP in Providence, Rhode Island. Data were collected at baseline, 3, and 6 months following PrEP initiation including total number of anal sex partners and condom use. A longitudinal mixed effects model assessed changes in number of partners and condom use over time, adjusting for age, race, and education. There was no statistically significant difference in total number of partners over time. There was a significant increase in number of condomless anal sex partners at the 6-month visit compared to baseline (mean change +1.31 partners, 95% confidence interval 0.09-2.53, P = 0.035). As condomless anal sex may increase following PrEP uptake, adherence counseling and efforts to retain patients in PrEP care, especially during periods of non-condom use, are important as PrEP is more widely implemented.

Keywords: Behavioral compensation; HIV; Implementation; Men who have sex with men; Pre-exposure prophylaxis.

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Conflict of interest statement

Conflicts of interest KHM has received unrestricted research grants from Gilead Sciences. LM reports institutional programmatic funding, consulting fees, and participation in on the speaker bureau from Gilead Sciences. CEO, ASN, MM, AA, RRP and PAC have declared no conflicts of interest.

Figures

Fig. 1
Fig. 1
A longitudinal mixed effects model demonstrating changes in a total number of sex partners and b number of condomless anal sex partners at baseline, three and six months after PrEP initiation
See this image and copyright information in PMC

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