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Review
. 2017 Dec;16(4):537-541.
doi: 10.1111/jocd.12308. Epub 2017 Feb 2.

Chemotherapy-induced alopecia management: Clinical experience and practical advice

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Review

Chemotherapy-induced alopecia management: Clinical experience and practical advice

Alfredo Rossi et al. J Cosmet Dermatol. 2017 Dec.

Abstract

Background: Chemotherapy-induced alopecia (CIA) is probably one of the most shocking aspects for oncological patients and underestimated by physicians. Among hair loss risk factors, there are treatment-related aspects such as drug dose, administration regimen, and exposure to X-rays, but also patient-related characteristics. To the best of our knowledge, no guidelines are available about CIA management.

Aims and methods: With this study, based on literature background and our clinical experience, we would like to propose a list of actions in order to estimate the risk of hair loss before starting chemotherapy and to manage this condition before, during, and after drug administration and to create a sort of practical guide for dermatologists and oncologists.

Results and conclusion: There is an urgent need for prospective studies to clarify the mechanistic basis of alopecia associated with these drugs and consequently to design evidence-based management strategies.

Keywords: chemotherapeutic drugs; hair loss; skin reactions.

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References

    1. Balagula Yevgeniy, Rosen Steven T., Lacouture Mario E. The emergence of supportive oncodermatology: The study of dermatologic adverse events to cancer therapies. J Am AcadDermatol. 2011 Sep;65(3):624–35. - PubMed
    1. Trüeb RM. Chemotherapy-induced hair loss. Skin Therapy Lett. 2010 Jul-Aug;15(7):5–7. - PubMed
    1. Paus R, Haslam IS, Sharov AA, Botchkarev VA. Pathobiology of chemotherapy-induced hair loss. Lancet Oncol. 2013 Feb;14(2):e50–9. - PubMed
    1. Miteva M, Misciali C, Fanti PA, Vincenzi C, Romanelli P, Tosti A. Permanent alopecia after systemic chemotherapy: a clinicopathological study of 10 cases. Am J Dermatopathol. 2011 Jun;33(4):345–50. - PubMed
    1. Rossi A, Iorio A, Scali E, Fortuna MC, Mari E, Maxia C, et al. Aromatase inhibitors induce 'male pattern hair loss' in women? Ann Oncol. 2013 Jun;24(6):1710–1. - PubMed

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